Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazole.
Vet Rec
; 148(15): 478-80, 2001 Apr 14.
Article
en En
| MEDLINE
| ID: mdl-11334074
ABSTRACT
The efficacy of fenbendazole for preventing an experimental infection of Encephalitozoon cuniculi and for eliminating the spores from the central nervous system of naturally infected rabbits was investigated. Fenbendazole (20 mg/kg bodyweight daily) was administered from seven days before until two or 21 days after rabbits had been infected orally with 10(6) spores of E. cuniculi. Both regimens were effective in preventing the establishment of the parasites, as demonstrated by negative parasitic-specific serology and by the failure to isolate the parasite from brain tissue. In naturally infected, seropositive rabbits, parasites were successfully isolated from seven of nine untreated animals, but not from the brain tissue of eight animals treated with fenbendazole-medicated pellets for four weeks.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encefalitozoonosis
/
Encephalitozoon cuniculi
/
Fenbendazol
/
Antinematodos
Límite:
Animals
Idioma:
En
Revista:
Vet Rec
Año:
2001
Tipo del documento:
Article
País de afiliación:
Suiza