Synthesis of branched cyclomaltooligosaccharide carboxylic acids (cyclodextrin carboxylic acids) by microbial oxidation.
Carbohydr Res
; 331(4): 423-30, 2001 Apr 23.
Article
en En
| MEDLINE
| ID: mdl-11398984
ABSTRACT
Novel branched cyclomaltooligosaccharide carboxylic acid (cyclodextrin carboxylic acid) derivatives were synthesized by microbial oxidation using Pseudogluconobacter saccharoketogenes to oxidize five types of branched cyclodextrins, including maltosyl beta-cyclodextrin (maltosyl-beta-CyD). For each novel cyclodextrin carboxylic acid derivative synthesized, the hydroxymethyl group of the terminal glucose residue in the branched part of the molecule was regiospecifically oxidized to a carboxyl group to give the corresponding uronic acid. In addition, the physicochemical properties of cyclomaltoheptaosyl-(6-->1)-alpha-D-glucopyranosyl-(4-->1)-alpha-D-glucopyranosiduronic acid (GUG-beta-CyD) (1) and its sodium salt were studied more extensively, as these compounds are most likely to have a practical application.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ciclodextrinas
/
Beta-Ciclodextrinas
Idioma:
En
Revista:
Carbohydr Res
Año:
2001
Tipo del documento:
Article
País de afiliación:
Japón