Chromosomal mapping of 18S-28S rRNA genes and 10 cDNA clones of human chromosome 1 in the musk shrew (Suncus murinus).
J Hered
; 92(3): 282-7, 2001.
Article
en En
| MEDLINE
| ID: mdl-11447248
ABSTRACT
The direct R-banding fluorescence in situ hybridization (FISH) method was used to map 18S-28S ribosomal RNA genes and 10 human cDNA clones on the chromosomes of the musk shrew (Suncus murinus). The chromosomal locations of 18S-28S ribosomal RNA genes were examined in the five laboratory lines and wild animals captured in the Philippines and Vietnam, and the genes were found on chromosomes 5, 6, 9, and 13 with geographic variation. The comparative mapping of 10 cDNA clones of human chromosome 1 demonstrated that human chromosome 1 consisted of at least three segments homologous to Suncus chromosomes (chromosomes 7, 10, and 14). This approach with the direct R-banding FISH method is useful for constructing comparative maps between human and insectivore species and for explicating the process of chromosomal rearrangements during the evolution of mammals.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Musarañas
/
Cromosomas Humanos Par 1
/
ARN Ribosómico 18S
/
ARN Ribosómico 28S
/
Mapeo Cromosómico
/
Hibridación Fluorescente in Situ
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Hered
Año:
2001
Tipo del documento:
Article
País de afiliación:
Japón