Rheological characterization of hydroalcoholic gels--15% ethanol--of Carbopol Ultrez 10.
Farmaco
; 56(5-7): 437-41, 2001.
Article
en En
| MEDLINE
| ID: mdl-11482773
ABSTRACT
The rheological behaviour of Carbopol Ultrez 10 ethanolic (15%) gels was studied as a function of two main variables pH (4.0-7.0) and the polymer concentration (0.1-0.5%). Flow curves of all hydroalcoholic gels were adjusted to the Ostwald model. Sigmoidal dose response functions were obtained to describe the pH dependence of consistency index of the systems. The concentration dependence of flow indexes was best adjusted to one-phase exponential decay functions. Finally, by substituting in the power law expression, an empirical model is given to estimate viscosities of gels for any value of pH and polymer concentration in the ranges evaluated. As a result, the influence of the variables on polymer network is meaningfully assessed by means of the obtained empirical parameters bottom value (Ymax), pH value required for a 50% polymer network development (pH50), and asymptotic flow index value for the fully structured gels (n(min)).
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polivinilos
/
Etanol
/
Geles
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Farmaco
Asunto de la revista:
FARMACOLOGIA
/
QUIMICA
Año:
2001
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
FR
/
FRANCE
/
FRANCIA
/
FRANÇA