Synthesis and biological activities of (Z) and (E) alpha-ethenyl acyclonucleosides.
Nucleosides Nucleotides Nucleic Acids
; 20(8): 1439-47, 2001 Aug.
Article
en En
| MEDLINE
| ID: mdl-11554537
ABSTRACT
Synthesis of Z and E ethenyl acyclonucleosides (6a-e and 7a-e) via Michael addition of nucleobases with the diethyl acetylenedicarboxylate is described. The structures of compounds have been confirmed by spectral data. New compounds were found to be inactive against DNA and RNA viruses.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Virus ARN
/
Virus ADN
/
Hidrocarburos Acíclicos
/
Nucleósidos
Límite:
Humans
Idioma:
En
Revista:
Nucleosides Nucleotides Nucleic Acids
Asunto de la revista:
BIOQUIMICA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Marruecos