April 2001: a 70 year old woman with recurrent meningioma.
Brain Pathol
; 11(4): 481-2, 487, 2001 Oct.
Article
en En
| MEDLINE
| ID: mdl-11556694
ABSTRACT
The April Case of the Month (COM). The contributors report a case of a 70 year-old woman with recurrent meningiomas, one of which showed rhabdoid and lipomatous differentiation. Histopathological study of the first and second previous resections showed only typical meningothelial meningioma. On the third craniotomy, a new tumor specimen showed an admixture of classic meningothelial meningioma with lipomatous and rhabdoid foci. Immunohistochemical studies showed diffuse reactivity for epithelial membrane antigen and vimentin, as well as focal positivity for desmin and smooth muscle actin in the areas with rhabdoid features and S100 protein in the lipomatous foci. The presence of these three different and concomitant histological patterns only in the third surgical resection might support a metaplastic origin and, also, corroborates the concept that rhabdoid features are suggestive of an aggressive behavior.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Meningioma
/
Recurrencia Local de Neoplasia
Límite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Brain Pathol
Asunto de la revista:
CEREBRO
/
PATOLOGIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Brasil