Biological and molecular characterization of a pigeon paramyxovirus type-1 isolate found in Argentina.
Avian Dis
; 45(3): 567-71, 2001.
Article
en En
| MEDLINE
| ID: mdl-11569728
ABSTRACT
In this report, we describe the biological and molecular characterization of a paramyxovirus type-1 (PPMV-1) isolate found in wild pigeons in an urban habitat in Buenos Aires, Argentina. Of the nine pigeons captured, three were moribund, and the other six showed diarrhea, ataxia, tremor, torticolis, and wing paralysis. The intracerebral pathogenicity index was 1.29, and the amino acid (aa) sequence at the fusion protein cleavage site was 112GRQ KRF117. These characteristics correspond to a virulent Newcastle disease virus isolate. Nevertheless, it was not possible to reproduce the disease in chickens experimentally although the chickens exhibited seroconversion after inoculation. On the other hand, pigeons inoculated with the isolate became sick. These results provide further evidence about the unusual pathogenicity of PPMV-1 for chickens and show once more the need for more biological determinations in these cases to arrive at a final conclusion.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Columbidae
/
Virus de la Enfermedad de Newcastle
/
Enfermedad de Newcastle
Límite:
Animals
País/Región como asunto:
America do sul
/
Argentina
Idioma:
En
Revista:
Avian Dis
Año:
2001
Tipo del documento:
Article
País de afiliación:
Argentina