Palatal development in Twirler mice.
Cleft Palate Craniofac J
; 38(6): 622-8, 2001 Nov.
Article
en En
| MEDLINE
| ID: mdl-11681996
ABSTRACT
OBJECTIVE:
The development of the secondary palate of Twirler (Tw) mice was characterized, and a quantitative coronal plane evaluation of the width and length of the craniofacial regions of homozygous mutant embryos was conducted. RESULTS ANDCONCLUSIONS:
The secondary palatal shelves were retarded in growth and the timing of elevation from a vertical to horizontal position. The homozygous Tw embryos, when compared with their wild-type littermates, also had a significantly wider midface. It is not surprising, therefore, that the short palatal shelves in a wide midface resulted in cleftings of the secondary palate observed in all homozygous Tw mice. These findings are consistent with similar studies in humans and other murine models.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hueso Paladar
/
Fisura del Paladar
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Cleft Palate Craniofac J
Asunto de la revista:
ODONTOLOGIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Estados Unidos