How to prolong postoperative analgesia after caudal anaesthesia with ropivacaine in children: S-ketamine versus clonidine.
Paediatr Anaesth
; 11(6): 679-83, 2001 Nov.
Article
en En
| MEDLINE
| ID: mdl-11696143
ABSTRACT
BACKGROUND:
The aim of the study was to determine whether caudal S-ketamine or clonidine prolonged analgesia together with ropivacaine.METHODS:
Sixty-three boys, aged 1-5 years, who were undergoing minor surgery, were allocated in order to receive one of three solutions for caudal anaesthesia. Group R received 2 mg x kg(-1) 0.2% ropivacaine; group C, 2 mg x kg(-1) 0.2% ropivacaine + clonidine 2 microg x kg(-1); and group K, 2 mg x kg(-1) 0.2% ropivacaine + S-ketamine 0.5 mg x kg(-1).RESULTS:
Postoperative analgesia assessed by CHEOPS lasted 701 min in group K (P < 0.05) compared with 492 min in group C and 291 min in group R. There were no significant differences between the groups for incidence of haemodynamic and respiratory alterations, motor block or sedation.CONCLUSIONS:
This study demonstrates that S-ketamine 0.5 mg x kg(-1) when added to 0.2% caudal ropivacaine provides better postoperative analgesia than clonidine without any clinically significant side-effect.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dolor Postoperatorio
/
Analgesia Epidural
/
Clonidina
/
Agonistas alfa-Adrenérgicos
/
Amidas
/
Ketamina
/
Anestésicos Disociativos
/
Anestésicos Locales
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Límite:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
Idioma:
En
Revista:
Paediatr Anaesth
Asunto de la revista:
ANESTESIOLOGIA
/
PEDIATRIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Italia