Rho-family GTPases in cadherin-mediated cell-cell adhesion.
Nat Rev Mol Cell Biol
; 2(12): 887-97, 2001 Dec.
Article
en En
| MEDLINE
| ID: mdl-11733768
ABSTRACT
Cell-cell adhesions are rearranged dynamically during tissue development and tumour metastasis. Recently, Rho-family GTPases, including RhoA, Rac1 and Cdc42, have emerged as key regulators of cadherin-mediated cell-cell adhesion. Following the identification and characterization of regulators and effectors of Rho GTPases, signal transduction pathways from cadherin to Rho GTPases and, in turn, from Rho GTPases to cadherin, are beginning to be clarified.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cadherinas
/
Adhesión Celular
/
Transactivadores
/
Proteínas de Unión al GTP rho
/
Proteínas Activadoras de ras GTPasa
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Nat Rev Mol Cell Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2001
Tipo del documento:
Article
País de afiliación:
Japón