Strategies for multiple sequence alignment.
Biotechniques
; 32(3): 572-4, 576, 578 passim, 2002 Mar.
Article
en En
| MEDLINE
| ID: mdl-11911661
ABSTRACT
We present an overview of multiple sequence alignments to outline the practical consequences for the choices among different techniques and parameters. We begin with a discussion of the scoring methods for quantifying the quality of a multiple sequence alignment, followed by a discussion of the algorithms implemented within a variety of multiple sequence alignment programs. We also discuss additional alignment details such as gap penalty and distance metrics. The paper concludes with a discussion on how to improve alignment quality and the limitations of the techniques described in this paper
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Alineación de Secuencia
/
Evolución Molecular
/
Modelos Genéticos
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Biotechniques
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos