[MR imaging of pancreatic lesions with Mn-DPDP. A histopathologic correlation]. / MRT von Läsionen des Pankreas mittels Mn-DPDP - Eine histopathologische Korrelation.
Rofo
; 174(7): 893-7, 2002 Jul.
Article
en De
| MEDLINE
| ID: mdl-12101481
ABSTRACT
PURPOSE:
To examine the diagnostic accuracy of pancreatic lesions using mangafodipir-trisodium (Mn-DPDP) enhanced MR imaging. The imaging results were correlated with the histopathological results. MATERIAL ANDMETHODS:
40 patients with suspicion of pancreatic carcinoma were examined with MRI before and after i. v. administration of Mn-DPDP (Philips Gyroscan ACS NT 1.5 T, phased array body-coil TSE T 2 with and without SPIR, TR 2000 ms, TE 120ms; FFE T 1 breathhold, TR 115 ms, TE 4.6 ms; MRCP, TR 6000 ms, TE 1200 ms; Teslascan i. v. 5 micromol Mn/kg; FFE T 1 breathhold SPIR, TR 140 ms, TE 4,6 ms). Two observers evaluated in consensus the number and characteristics of focal pancreatic lesions. The MR findings were correlated with histopathological findings retrospectively.RESULTS:
The following lesions were found adenocarcinoma (19), pancreatitis (8), adenocarcinoma within pancreatitis (3), insulinoma (2), hematoma (1), papillitis stenosans (1), signet ring cell carcinoma (1), metastasis of rectal carcinoma (1), papillary mesothelioma (1). In three patients there was no pathological finding. Mn-DPDP enhanced MRI showed a sensitivity of 100 % and a specificity of 56 %.CONCLUSION:
Mn-DPDP enhanced MRI in conjunction with MRCP showed a high sensitivity for the detection of pancreatic lesions. However, the specificity is low, thus recommending Mn-DPDP enhanced MRI only as a complementary imaging method.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Pancreáticas
/
Pancreatitis
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Fosfato de Piridoxal
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Ampolla Hepatopancreática
/
Imagen por Resonancia Magnética
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Aumento de la Imagen
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Ácido Edético
/
Neoplasias del Conducto Colédoco
/
Medios de Contraste
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
De
Revista:
Rofo
Año:
2002
Tipo del documento:
Article
País de afiliación:
Alemania
Pais de publicación:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY