Amelioration of relapsing polychondritis in a child treated with oral collagen.
Am J Med Sci
; 324(2): 101-3, 2002 Aug.
Article
en En
| MEDLINE
| ID: mdl-12187928
ABSTRACT
Relapsing polychondritis (RP) is a disease characterized by inflammation and the destruction of cartilage. The detection of antibodies to native type II collagen (CII) in the sera of some patients with relapsing polychondritis suggests that autoimmunity to this cartilage specific protein plays a role in the pathogenesis of the disease. RP is so rare that controlled therapeutic trials have not been carried out. We describe herein a child with RP who had amelioration of symptoms and a deviation in the cellular immune response to CII after being treated with daily oral CII as a toleragen.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Policondritis Recurrente
/
Procolágeno
/
Colágeno Tipo II
Límite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
Am J Med Sci
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos