Different striatal dopamine D2 receptor occupancy in alcohol dependent patients with or without physical withdrawal symptoms --a study using IBZM-SPECT.
J Neural Transm (Vienna)
; 109(9): 1215-9, 2002 Sep.
Article
en En
| MEDLINE
| ID: mdl-12203049
ABSTRACT
Ten male patients with type I alcohol dependency fulfilling DSM-IV criteria for alcohol dependency were investigated twice using IBZM-SPECT after alcohol withdrawal (day 2 and day 28 after withdrawal). Five patients had a history of physical withdrawal symptoms, 5 patients had no such history. The group with physical withdrawal symptoms showed higher IBZM binding in both scans indicating differences of dopaminergic neurotransmission in different subtypes of alcohol dependency.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Abstinencia a Sustancias
/
Dopamina
/
Receptores de Dopamina D2
/
Neostriado
/
Trastornos del Sistema Nervioso Inducidos por Alcohol
/
Etanol
/
Neuronas
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Neural Transm (Vienna)
Año:
2002
Tipo del documento:
Article