A new method for synthesis of 7-deoxytaxane analogues by hydrogenation of delta(6,7)-taxane derivatives.

Takeda, Yasuyuki; Yoshino, Toshiharu; Uoto, Kouichi; Terasawa, Hirofumi; Soga, Tsunehiko

Takeda, Yasuyuki; Yoshino, Toshiharu; Uoto, Kouichi; Terasawa, Hirofumi; Soga, Tsunehiko.

Afiliación

Takeda Y; Medicinal Chemistry Research Laboratory, Daiichi Pharmaceutical Co., Ltd., Tokyo R&D Center, Japan.

Chem Pharm Bull (Tokyo) ; 50(10): 1398-400, 2002 Oct.

Article en En | MEDLINE | ID: mdl-12372874

ABSTRACT

ABSTRACT

A new method for the synthesis of 7-deoxytaxane analogues has been established through hydrogenation of Delta(6,7)-taxane derivatives. Among several catalysts examined, Pd-C was found to be a most effective catalyst for the preparation of target compound.

Asunto(s)

Hidrocarburos Aromáticos con Puentes/síntesis química; Taxoides; Hidrocarburos Aromáticos con Puentes/química; Hidrogenación

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hidrocarburos Aromáticos con Puentes / Taxoides Idioma: En Revista: Chem Pharm Bull (Tokyo) Año: 2002 Tipo del documento: Article País de afiliación: Japón

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