Your browser doesn't support javascript.
loading
The implication of a reduced-dose hepatitis B vaccination schedule in low risk newborns.
Lee, S S; Young, B W Y; Wong, K H; Lim, W L.
Afiliación
  • Lee SS; Department of Health, Hong Kong SAR Government, Hong Kong, China. ss_lee@dh.gov.hk
Vaccine ; 20(31-32): 3752-4, 2002 Nov 01.
Article en En | MEDLINE | ID: mdl-12399205
Five hundred and seventy-four babies born to HBsAg negative mothers in Hong Kong received either a regular (5 micro g) or reduced (2.5 micro g) three-dose regimen of recombinant hepatitis B vaccine. A significantly higher anti-HBs positivity rate (>or=10 mIU/ml), geometric mean titer (GMT) and the maintenance of a high anti-HBs level (>or=100 mIU/ml) were observed with the regular-dose regimen. The differences persisted, however, only up to 1 year post-vaccination. Over an 8-year period, only 1% of the vaccinees demonstrated anti-HBc seroconversion and none had become HBsAg positive. The long-term efficacy of the reduced-dose regimen was confirmed, even in an HBV endemic population.
Asunto(s)
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / Vacunas contra Hepatitis B / Hepatitis B / Anticuerpos contra la Hepatitis B Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Newborn Idioma: En Revista: Vaccine Año: 2002 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / Vacunas contra Hepatitis B / Hepatitis B / Anticuerpos contra la Hepatitis B Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Newborn Idioma: En Revista: Vaccine Año: 2002 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos