[Transmission of hepatitis C virus in pregnant women]. / Transmisión del virus de la hepatitis C en gestantes.
Med Clin (Barc)
; 120(1): 10-3, 2003 Jan 18.
Article
en Es
| MEDLINE
| ID: mdl-12525298
ABSTRACT
BACKGROUND AND OBJECTIVE:
Our goal was to determine the prevalence of hepatitis C virus infection in pregnant women from Asturias as well as the vertical transmission rate. PATIENTS ANDMETHOD:
This was a prospective study of consecutive pregnant women from the 5th Health Area of Principado de Asturias (Northern Spain). We determined the prevalence of hepatitis C virus infection in the first trimester of pregnancy and the rate of mother-to-child transmission. Time period was August 1997-December 1998. Children were followed from birth to 18-24 months of age. Methods included anti-HVC, PCR-RNA-HVC, genotype and viral load at delivery of all positive women; and anti-HVC and PCR-RNA-HVC at birth, 3, 6, 12 and 18 months of age of their children.RESULTS:
Out of 2442 consecutive pregnant women, 30 were anti-HVC positive (prevalence 1.23% of pregnancies and 1.20% of women); 24 of them were PCR-RNA-HVC positive. There were 30 anti-HVC positive children. All but one lost their antibodies (vertical transmission rate 3.3%).CONCLUSIONS:
The prevalence of hepatitis C virus infection was 1.20% of women from our Health Area. Vertical transmission rate was 3.3% among HVC infected, non-selected mothers.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complicaciones Infecciosas del Embarazo
/
Hepatitis C
/
Hepacivirus
/
Transmisión Vertical de Enfermedad Infecciosa
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Infant
/
Newborn
/
Pregnancy
Idioma:
Es
Revista:
Med Clin (Barc)
Año:
2003
Tipo del documento:
Article