Cytokines and other biologic agents as immunotherapeutics for cutaneous T-cell lymphoma.
Adv Dermatol
; 18: 29-43, 2002.
Article
en En
| MEDLINE
| ID: mdl-12528401
ABSTRACT
Cutaneous T-cell lymphomas (CTCLs) are a group of skin-invasive malignancies of clonally derived T lymphocytes. Mycosis fungoides and Sézary syndrome, characterized by the proliferation of CD4+ T cells, are the most common forms of CTCL. Among these latter disorders, the host antitumor response appears to play an important role in disease control. Thus, systemic therapeutic agents are used in an effort to augment the host antitumor response while selectively targeting the malignant cells. Both new and old biologic response-modifying treatment options currently used to treat CTCL are reviewed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Citocinas
/
Linfoma Cutáneo de Células T
/
Inmunoterapia
Límite:
Humans
Idioma:
En
Revista:
Adv Dermatol
Asunto de la revista:
DERMATOLOGIA
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos