Simple and efficient solid support scavenging of excess acyl donors after enzymatic acylations in organic solvents.
Biotechnol Bioeng
; 82(4): 379-85, 2003 May 20.
Article
en En
| MEDLINE
| ID: mdl-12632393
ABSTRACT
A simple and efficient method for removing excess acyl donors following enzymatic acylations in organic solvents was developed. This method is based on selective chemical scavenging of acyl donors using an amino-functionalized solid support, and does not affect the desired acylated product. A wide variety of different acyl donors, including vinyl and trifluoroethyl esters and vinyl carbonates, can be quantitatively removed by this method, thus providing a simple and highly efficient tool for purification of reaction products after enzymatic acylation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Solventes
/
Compuestos de Vinilo
/
Depuradores de Radicales Libres
/
Lipasa
Tipo de estudio:
Evaluation_studies
Idioma:
En
Revista:
Biotechnol Bioeng
Año:
2003
Tipo del documento:
Article
País de afiliación:
Estados Unidos