Cutaneous granulomas as the first manifestation of Hodgkin's disease.
Eur J Dermatol
; 13(3): 299-301, 2003.
Article
en En
| MEDLINE
| ID: mdl-12804995
ABSTRACT
We report the case of a 64-year-old male in whom fever, cutaneous rash and hepatomegaly were the first manifestations of Hodgkin disease (HD). Histologically a dense lymphohistiocytic infiltrate with a granulomatous pattern was found in the skin infiltrate. A computed tomography scan revealed hepatosplenomegaly and a small retroperitoneal lymphadenopathy. An hepatic percutaneous biopsy showed a granulomatous infiltration with typical Reed-Sternberg cells. Cutaneous manifestations of HD are briefly reviewed. The authors underline that granulomatous infiltration of the skin as the first manifestation of lymphoma is a very rare feature. We also discuss the possible pathogenic mechanisms of skin granulomas.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Enfermedad de Hodgkin
/
Granuloma
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur J Dermatol
Asunto de la revista:
DERMATOLOGIA
Año:
2003
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
FR
/
FRANCE
/
FRANCIA
/
FRANÇA