Synthesis and fungicidal activity of lipophylic N- and O-acyl derivatives of beta-hydroxy DL-alpha-amino acids.
Z Naturforsch C J Biosci
; 58(5-6): 366-70, 2003.
Article
en En
| MEDLINE
| ID: mdl-12872931
ABSTRACT
Synthesis of N- and O-acyl derivatives of DL-serine and threo-DL-phenylserine was accomplished by a regioselective acylation of the corresponding amino acid. The residues introduced into amino acid structure contain hydrophobic long chain or aromatic, namely lauroyl, myristoyl and phenylacetyl moieties. The fungicidal activity against six strains of fungi was studied. Several compounds were found to be effective against growth of fungi, and O-myristoyl-DL-serine 2 and N-phenylacetyl-threo-DL-phenylserine 8 completely inhibited the growth of the mycelium of the fungus Verticillium dahliae.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aminoácidos
/
Hidroxiácidos
/
Antifúngicos
Idioma:
En
Revista:
Z Naturforsch C J Biosci
Año:
2003
Tipo del documento:
Article
País de afiliación:
Lituania