Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fields.
Mech Ageing Dev
; 124(7): 847-50, 2003 Jul.
Article
en En
| MEDLINE
| ID: mdl-12875748
ABSTRACT
Several studies indicating a decline of DNA repair efficiency with age raise the question, if senescence per se leads to a higher susceptibility to DNA damage upon environmental exposures. Cultured fibroblasts of six healthy donors of different age exposed to intermittent ELF-EMF (50 Hz sinus, 1 mT) for 1-24 h exhibited different basal DNA strand break levels correlating with age. The cells revealed a maximum response at 15-19 h of exposure. This response was clearly more pronounced in cells from older donors, which could point to an age-related decrease of DNA repair efficiency of ELF-EMF induced DNA strand breaks.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Daño del ADN
/
Envejecimiento
/
Campos Electromagnéticos
/
Fibroblastos
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Mech Ageing Dev
Año:
2003
Tipo del documento:
Article
País de afiliación:
Austria