Increase in severity of graft versus host disease by cytomegalovirus.
J Clin Pathol
; 45(6): 542-4, 1992 Jun.
Article
en En
| MEDLINE
| ID: mdl-1320637
ABSTRACT
An allogeneic transplant recipient developed severe graft versus host disease (GvHD) 48 days after transplantation that was concomitant with a cytomegalovirus (CMV) viraemia, from which she subsequently died. CMV infection was detected in blood by the polymerase chain reaction and later in tissue by immunohistochemical techniques. CMV should be considered in patients in whom GvHD does not respond to appropriate treatment, and this case suggests that herpes viruses may increase the severity of GvHD by synergistically enhancing the graft versus host reaction.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Viremia
/
Infecciones por Citomegalovirus
/
Enfermedad Injerto contra Huésped
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
J Clin Pathol
Año:
1992
Tipo del documento:
Article