Neuronal growth and the Steiner problem.
Riv Biol
; 85(3-4): 405-18, 1992.
Article
en En
| MEDLINE
| ID: mdl-1341834
ABSTRACT
In this paper we conjecture that neuronal networks develop following an optimality principle. We point out that a neuronal outgrowth in culture may be seen as the solution of a classical optimization problem:
the "Steiner Problem". A neuron might grow minimizing a "cost", which may be determined by the viscoelastic properties of the neuron cytoplasm. We then discuss the role of chemiotactic factors such as the Nerve Growth Factor (NGF) in an optimized neuronal development in vivo. Finally we suggest, with some mathematical arguments, that the optimization of the elastic forces in the growing neuron may give rise to a "fractal" structure.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Modelos Biológicos
/
Red Nerviosa
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Riv Biol
Año:
1992
Tipo del documento:
Article
País de afiliación:
Italia