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Generalized papular xanthomatosis in mycosis fungoides.
Darwin, B S; Herzberg, A J; Murray, J C; Olsen, E A.
Afiliación
  • Darwin BS; Department of Medicine, Duke University Medical Center, Durham, NC 27710.
J Am Acad Dermatol ; 26(5 Pt 2): 828-32, 1992 May.
Article en En | MEDLINE | ID: mdl-1377209
Xanthomas can occur in association with underlying lymphoproliferative disease, or they can result from lipid deposition in damaged or altered skin. We report a case of generalized papular xanthomas that developed in a patient with Sézary syndrome. The xanthomas were composed of foamy histiocytes that were shown by immunoperoxidase staining to be of the monocyte/macrophage lineage. Electron microscopic studies revealed lipid vacuoles, lysosomes, and myelin figures but no Birbeck granules, features that are consistent with a non-X histiocytosis. Generalized papular xanthomatosis has not been previously described in a patient with cutaneous T-cell lymphoma.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Xantomatosis / Síndrome de Sézary Límite: Aged / Female / Humans Idioma: En Revista: J Am Acad Dermatol Año: 1992 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Xantomatosis / Síndrome de Sézary Límite: Aged / Female / Humans Idioma: En Revista: J Am Acad Dermatol Año: 1992 Tipo del documento: Article Pais de publicación: Estados Unidos