Preliminary report on seroepidemiology of HCV and HBV infection in northern China.
Chin Med J (Engl)
; 105(3): 209-11, 1992 Mar.
Article
en En
| MEDLINE
| ID: mdl-1395840
ABSTRACT
1 141 serum samples from various population groups in north China were examined for C100-3Ab by ELISA. Antibody to C100-3 antigen derived from HCV genome (C100-3A) and HBsAg were measured in 438 normal population in Beijing. The C100-3Ab positive rate was 2.1% and the HBsAg positive rate was 2.5%. There is increased occurrence with age. In 649 cases of chronic liver diseases, the HBsAg positive rate was 87.1% in chronic persistent hepatitis (CPA), 88.8% in chronic active hepatitis (CAH), 64.9% in liver cirrhosis (LC) and 67.3% in hepatocellular carcinoma (HCC). The C100-3Ab positive rate was 10.5% (CPH), 12.1% (CAH), 42.6% (LC) and 38.4% (HCC). It is noteworthy that the C100-3Ab positive rate significantly increased with disease progression from CPH to CAH, LC and HCC. Prevalence of cases positive for both C100-3Ab and HBsAg was 0% in the normal population, 6.7% in CPH, 8.4% in CAH, 31.1% in LC and 28.8% in HCC. Investigation of patients with HCV infection showed that only 36.8% had blood transfusions. HCV and HBV infection may play important pathogenic roles in CPH, CAH, LC and HCC in north China.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hepatitis C
/
Proteínas no Estructurales Virales
/
Anticuerpos contra la Hepatitis C
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Hepatitis B
/
Antígenos Virales
Tipo de estudio:
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
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Infant
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Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Chin Med J (Engl)
Año:
1992
Tipo del documento:
Article