Metabolism of very low density lipoproteins in the pig. An in vivo study.
Int J Biochem
; 24(10): 1591-7, 1992 Oct.
Article
en En
| MEDLINE
| ID: mdl-1397485
1. The metabolism of apolipoprotein B (apoB) was investigated in pigs injected with [125I]very low density lipoproteins (VLDL) to determine to which extent the two distinct low density lipoprotein subclasses (LDL1 and LDL2) derive from VLDL. 2. The lipoproteins were isolated by density gradient ultracentrifugation and the transfer of radioactivity from VLDL into LDL1 and LDL2 apoB was measured. 3. Only a minor portion of VLDL apoB was converted to LDL1 (7.7 +/- 3.2%) and LDL2 (3.6 +/- 1.5%), respectively. Thus, we conclude that the major portion of LDL, especially LDL2, is synthesized independently from VLDL catabolism.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lipoproteínas LDL
/
Lipoproteínas VLDL
Límite:
Animals
Idioma:
En
Revista:
Int J Biochem
Año:
1992
Tipo del documento:
Article
País de afiliación:
Austria
Pais de publicación:
Reino Unido