Effect of hemodialysis on lipid peroxidation and antioxidant system in patients with chronic renal failure.
Metabolism
; 41(11): 1229-32, 1992 Nov.
Article
en En
| MEDLINE
| ID: mdl-1435296
ABSTRACT
Plasma lipid peroxidation, activity of erythrocyte superoxide dismutase (SOD) and catalase, and serum antioxidant activity (AOA) in uremic patients were examined before and after hemodialysis. An increased level of lipid peroxidation, a decreased serum AOA level, and elevated SOD and normal catalase activity before hemodialysis were observed in uremic patients compared with controls. Hemodialysis was found to produce increased lipid peroxidation, a simultaneous decrease of SOD activity, and lack of any changes in serum AOA and erythrocyte catalase. It is suggested that intensification of lipid peroxidation during hemodialysis could account for accelerated progress of atherosclerosis in patients with renal insufficiency.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Peroxidación de Lípido
/
Diálisis Renal
/
Fallo Renal Crónico
/
Antioxidantes
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Metabolism
Año:
1992
Tipo del documento:
Article
País de afiliación:
Polonia
Pais de publicación:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA