Dynamic balance changes between elastase and antiprotease in the early stages after smoke inhalation injury.
Burns
; 18(5): 362-7, 1992 Oct.
Article
en En
| MEDLINE
| ID: mdl-1445624
ABSTRACT
Following the use of a rabbit smoke inhalation injury model established in this institute, there were marked reductions in elastase activities in neutrophils and alveolar macrophages; rapid increases in elastase activity in broncho-alveolar lavage fluid (BALF); reductions of serum trypsin inhibitory capacity; a decrease of Pao2 and an increase of PaCO2, and marked increases of lung water volume. Significant correlations were found between the increased extravascular lung water content and the rising elastase activity in BALF. It seems probable that the imbalance between elastase and antiprotease played an important role in the development of acute lung injury after smoke inhalation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inhibidores de Proteasas
/
Elastasa Pancreática
/
Lesión por Inhalación de Humo
Límite:
Animals
Idioma:
En
Revista:
Burns
Año:
1992
Tipo del documento:
Article
País de afiliación:
China