A whole genome screen for association in Polish multiple sclerosis patients.
J Neuroimmunol
; 143(1-2): 107-11, 2003 Oct.
Article
en En
| MEDLINE
| ID: mdl-14575925
ABSTRACT
We have performed the first systematic search for MS susceptibility genes completed in the Polish population. This screen was performed using 6000 microsatellite markers typed in pooled DNA from cases (n=200), controls (n=200) and trio families (n=129). Five associated markers are identified, one (D6S2444) from the HLA region and four are from novel regions not previously associated with MS, 2p16 (D2S2153), 3p13 (D3S3568), 7p22 (D7S2521) and 15q26 (D15S649).
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Genoma Humano
/
Pruebas Genéticas
/
Predisposición Genética a la Enfermedad
/
Esclerosis Múltiple
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Neuroimmunol
Año:
2003
Tipo del documento:
Article
País de afiliación:
Polonia