[The mechanism of the antioxidant action of D-penicillamine]. / Mekhanizm antioksidantnogo deistviia D-penitsillamina.
Eksp Klin Farmakol
; 55(3): 42-3, 1992.
Article
en Ru
| MEDLINE
| ID: mdl-1458162
ABSTRACT
The mechanism of the antioxidative effect of D-penicillamine was studied under the conditions of NADPH- and CCl4-dependent lipid peroxidation in microsomes of rat liver and adrenalin autooxidation reaction. The antioxidative action of the drug was shown to be due to both its chelating properties and direct anti-radical influence. The chelating effect was more pronounced and depended on the concentration of ferric ions in the medium.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Penicilamina
/
Antioxidantes
Límite:
Animals
Idioma:
Ru
Revista:
Eksp Klin Farmakol
Asunto de la revista:
FARMACOLOGIA
Año:
1992
Tipo del documento:
Article