Translocation (12;17)(p11-12;q11-12): a recurrent primary rearrangement in acute leukemia.
Cancer Genet Cytogenet
; 64(1): 27-9, 1992 Nov.
Article
en En
| MEDLINE
| ID: mdl-1458446
ABSTRACT
We identified two patients with acute leukemia in relapse (one lymphoblastic and the other with evidence of mixed lymphoid-myeloid differentiation) with t(12;17)(p12;q11) as the primary karyotypic abnormality. There are six previously reported cases of acute leukemia with an identical or similar translocation. To our knowledge, t(12;17) has not been reported in other forms of neoplasia. A review of these cases suggests that t(12;17) carries a poor prognosis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Translocación Genética
/
Cromosomas Humanos Par 12
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Cromosomas Humanos Par 17
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Leucemia Mieloide Aguda
/
Leucemia Linfoide
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
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Adult
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Humans
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Male
Idioma:
En
Revista:
Cancer Genet Cytogenet
Año:
1992
Tipo del documento:
Article
Pais de publicación:
EEUU
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ESTADOS UNIDOS
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ESTADOS UNIDOS DA AMERICA
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EUA
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UNITED STATES
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UNITED STATES OF AMERICA
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US
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USA