High-sensitive C-reactive protein level and oxidative stress-related status in former athletes in relation to traditional cardiovascular risk factors.
Atherosclerosis
; 171(2): 321-6, 2003 Dec.
Article
en En
| MEDLINE
| ID: mdl-14644403
ABSTRACT
OBJECTIVE:
To analyze systemic and cellular oxidative stress-related indices as well as C-reactive protein level in former top-level athletes in relation to traditional cardiovascular risk factors.METHODS:
A cross-sectional study was performed in 53 former male athletes and 25 sedentary controls (age range 39-59 years). We measured anthropometric factors (BMI, fat percentage, WHR), resting blood pressure (SBP, DBP), serum cholesterol (CHOL), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglycerides (TG), total antioxidant status (TAS), oxidized LDL-C (oxLDL), diene conjugates (DC), glutathione redox status, high-sensitive C-reactive protein (hsCRP), and leisure-time physical activity.RESULTS:
Physically active former athletes had significantly lower mean overweight (BMI, fat percentage, WHR), better spectrum of atherogenesis indicators (CHOL, HDL-C, TG, TGHDL-C ratio) and lower oxidative stress (oxLDL, oxLDLLDL-C ratio, DC) values than sedentary ex-athletes. No significant differences in these variables were found between the sedentary ex-athletes and control group. Significant associations were found between physical activity (METs), SBP, DBP, hypertension, CHOL, HDL-C, TG, TGHDL-C ratio, oxLDL, oxLDLLDL-C ratio, DC and hsCRP.CONCLUSIONS:
A physically active lifestyle is related to a lower cardiovascular disease (CVD) risk profile including a substantially lower systemic and cellular oxidative stress status as well as C-reactive protein level in middle-aged men.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Deportes
/
Proteína C-Reactiva
/
Enfermedades Cardiovasculares
/
Estrés Oxidativo
/
HDL-Colesterol
/
LDL-Colesterol
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Atherosclerosis
Año:
2003
Tipo del documento:
Article
País de afiliación:
Estonia