[A case of secondary myelodysplastic syndrome following chemotherapy for lung cancer].
Nihon Kyobu Shikkan Gakkai Zasshi
; 30(10): 1825-9, 1992 Oct.
Article
en Ja
| MEDLINE
| ID: mdl-1464983
ABSTRACT
A case of secondary myelodysplastic syndrome (MDS) following chemotherapy for lung cancer is reported. A 78-year-old man, with a smoking history of 20 cigarettes/day for 55 years, was incidentally, diagnosed as having stage IV squamous cell carcinoma of the lung in 1987 during admission for transurethral resection of bladder cancer. He received combination chemotherapy of mitomycin C, vincristin, and cisplatin for his lung cancer between July and September 1988. His clinical course remained almost stable until October 1989, when his blood count showed severe anemia and thrombocytopenia. He was diagnosed as having secondary MDS induced by cytotoxic agents used for the treatment of lung cancer, based on the dysplastic findings of precursor cells in the bone marrow and the chromosome abnormality of 51XY, +8, +9, +21, 3p-, 5q-, +2mar. He died of infection with the progression of MDS in March 1990.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndromes Mielodisplásicos
/
Carcinoma de Células Escamosas
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Neoplasias Pulmonares
Límite:
Aged
/
Humans
/
Male
Idioma:
Ja
Revista:
Nihon Kyobu Shikkan Gakkai Zasshi
Año:
1992
Tipo del documento:
Article
País de afiliación:
Japón