Vulvar melanoma: diffuse melanosis and metastasis to the placenta.
J Am Acad Dermatol
; 50(2): 293-8, 2004 Feb.
Article
en En
| MEDLINE
| ID: mdl-14726891
ABSTRACT
Mucocutaneous melanoma, including vulvar melanoma, is rare and has a worse prognosis and higher recurrence rate than traditional cutaneous melanoma. Diffuse cutaneous melanosis is another rare clinical presentation of metastatic melanoma. It is essential for dermatologists to be alerted to rare presentations of melanoma, to facilitate early detection. We present the first case to our knowledge of metastatic vulvar melanoma with diffuse cutaneous melanosis in a pregnant young woman. Despite the occurrence of placental metastasis, a healthy, unaffected baby was born. This case exemplifies the aggressiveness of vulvar melanoma. The genitalia should be included in routine total body skin examinations. Pregnant women with generalized melanosis may be at increased risk for placental metastasis of melanoma. Pregnancy does not alter the incidence or prognosis of melanoma; however, patients with a poor prognosis or high recurrence risk should be informed of potential pregnancy complications associated with melanoma recurrence or metastasis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Placentarias
/
Complicaciones Neoplásicas del Embarazo
/
Neoplasias Cutáneas
/
Neoplasias de la Vulva
/
Melanoma
/
Melanosis
Tipo de estudio:
Prognostic_studies
/
Screening_studies
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
J Am Acad Dermatol
Año:
2004
Tipo del documento:
Article
País de afiliación:
Estados Unidos