Decomposition of alpha-hydroxyaryl ketones and characterization of some unusual products.
J Pharm Sci
; 81(12): 1199-203, 1992 Dec.
Article
en En
| MEDLINE
| ID: mdl-1491340
ABSTRACT
Alpha-Hydroxyaryl ketones such as 2-hydroxypropiophenone and 1-(2,4-difluorophenyl)-2-hydroxy-1-propanone, the key intermediates in the preparation of antifungal agents, decompose into oxidized, rearranged, and condensed products. These products were isolated and characterized. The possible mechanisms for the formation of the products are discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cetonas
Idioma:
En
Revista:
J Pharm Sci
Año:
1992
Tipo del documento:
Article