Sample size calculator for cluster randomized trials.
Comput Biol Med
; 34(2): 113-25, 2004 Mar.
Article
en En
| MEDLINE
| ID: mdl-14972631
ABSTRACT
Cluster randomized trials, where individuals are randomized in groups are increasingly being used in healthcare evaluation. The adoption of a clustered design has implications for design, conduct and analysis of studies. In particular, standard sample sizes have to be inflated for cluster designs, as outcomes for individuals within clusters may be correlated; inflation can be achieved either by increasing the cluster size or by increasing the number of clusters in the study. A sample size calculator is presented for calculating appropriate sample sizes for cluster trials, whilst allowing the implications of both methods of inflation to be considered.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Análisis por Conglomerados
/
Ensayos Clínicos Controlados Aleatorios como Asunto
Tipo de estudio:
Clinical_trials
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Comput Biol Med
Año:
2004
Tipo del documento:
Article