Detection of antibodies to toxin-coregulated pili in sera from cholera patients.
Infect Immun
; 72(3): 1824-7, 2004 Mar.
Article
en En
| MEDLINE
| ID: mdl-14977996
Monoclonal antibodies (MAbs) were prepared against toxin-coregulated pili (TCP) isolated from Vibrio cholerae O1 El Tor. Despite their limited bactericidal potential, two MAbs were able to mediate biotype-specific protection against experimental cholera in infant mice. These MAbs were used in immunoblotting studies to assess seroconversion to El Tor TCP following cholera. Clear anti-pilus responses were observed in five of nine patients.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Toxinas Bacterianas
/
Cólera
/
Fimbrias Bacterianas
/
Vibrio cholerae O1
/
Anticuerpos Antibacterianos
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Infect Immun
Año:
2004
Tipo del documento:
Article
País de afiliación:
Australia
Pais de publicación:
Estados Unidos