Adhesion of membranes with competing specific and generic interactions.
Eur Phys J E Soft Matter
; 8(1): 59-66, 2002 May.
Article
en En
| MEDLINE
| ID: mdl-15010982
ABSTRACT
Biomimetic membranes in contact with a planar substrate or a second membrane are studied theoretically. The membranes contain specific adhesion molecules (stickers) which are attracted by the second surface. In the absence of stickers, the trans-interaction between the membrane and the second surface is assumed to be repulsive at short separations. It is shown that the interplay of specific attractive and generic repulsive interactions can lead to the formation of a potential barrier. This barrier induces a line tension between bound and unbound membrane segments which results in lateral phase separation during adhesion. The mechanism for adhesion-induced phase separation is rather general, as is demonstrated by considering two distinct cases involving i) stickers with a linear attractive potential, and ii) stickers with a short-ranged square-well potential. In both cases, membrane fluctuations reduce the potential barrier and, therefore, decrease the tendency of phase separation.
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01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Eur Phys J E Soft Matter
Asunto de la revista:
BIOFISICA
Año:
2002
Tipo del documento:
Article
País de afiliación:
Alemania
Pais de publicación:
FR
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FRANCE
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FRANCIA
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FRANÇA