Vitamin B-6 status of breast-fed neonates: influence of pyridoxine supplementation on mothers and neonates.
Am J Clin Nutr
; 56(3): 548-58, 1992 Sep.
Article
en En
| MEDLINE
| ID: mdl-1503068
ABSTRACT
Vitamin B-6 concentrations in human milk are known to respond rapidly to changes in maternal vitamin B-6 intake. In this study, mothers were supplemented during the first 28 d of lactation with 2 or 27 mg pyridoxine (PN)-HCl/d and a subgroup of breast-fed infants of the 2-mg/d-supplemented mothers were supplemented with 0.4 mg PN-HCl/d. Vitamin B-6 intakes of breast-fed infants reflected the amount of their mother's supplement; intakes were highest for the vitamin-supplemented infants. Vitamin B-6 intake of mothers was a strong indicator of infant vitamin B-6 status. Vitamin intake of infants correlated significantly with five measures of vitamin B-6 status. Plasma pyridoxal-5'-phosphate (PLP) concentrations and birth weight were the strongest predictors of infant growth that were examined. Alkaline phosphatase activity in the mother's milk and infant plasma reflected pyridoxal-PLP ratios in these fluids, suggesting that the enzyme acts in regulating circulating vitamer concentrations.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piridoxina
/
Lactancia Materna
/
Leche Humana
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Female
/
Humans
/
Newborn
Idioma:
En
Revista:
Am J Clin Nutr
Año:
1992
Tipo del documento:
Article
País de afiliación:
India