Pilot trial of albuterol in Duchenne and Becker muscular dystrophy.
Neurology
; 62(6): 1006-8, 2004 Mar 23.
Article
en En
| MEDLINE
| ID: mdl-15037714
ABSTRACT
The authors conducted a randomized, crossover, double-blind, placebo-controlled pilot study of albuterol in nine boys with dystrophinopathies. Primary outcomes were 1) isometric knee extensor and flexor strength; and 2) manual muscle testing (MMT). Isometric knee extensor strength and MMT scores were significantly higher in patients taking albuterol vs placebo. Therefore, 12-week treatment with extended-release albuterol may increase strength in patients with dystrophinopathies. A larger, double-blind, randomized study is necessary to confirm these results.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Agonistas Adrenérgicos beta
/
Distrofia Muscular de Duchenne
/
Albuterol
Tipo de estudio:
Clinical_trials
/
Guideline
/
Observational_studies
/
Prognostic_studies
Límite:
Child
/
Humans
/
Male
Idioma:
En
Revista:
Neurology
Año:
2004
Tipo del documento:
Article
País de afiliación:
Estados Unidos