The identification and quantitation of the major metabolites of ethylamphetamine, produced by rabbit liver microsomal preparations.
J Pharm Pharmacol
; 29(2): 89-65, 1977 Feb.
Article
en En
| MEDLINE
| ID: mdl-15071
ABSTRACT
Amphetamine (I), 1-phenylpropan-2-ol (III), phenylacetone (V), N-hydroxyethylamphetamine (VII), and alpha-methyl-N-(1'-phenylprop-2'-yl)nitrone (VIII) were obtained as metabolic products from the incubation of ethylamphetamine (II) with fortified male rabbit liver 9000 g supernatant fractions. These metabolites were identified by comparing their t.l.c., g,l.c. and g.l.c.-m.s. behaviour to that of reference compounds. A method for the quantitative analysis of the metabolites in mixtures using g.l.c. techniques is described.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Anfetaminas
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
J Pharm Pharmacol
Año:
1977
Tipo del documento:
Article