Simulation of compartmental models for kinetic data from a positron emission tomograph.
Comput Methods Programs Biomed
; 37(3): 205-14, 1992 Apr.
Article
en En
| MEDLINE
| ID: mdl-1511605
ABSTRACT
Linear compartmental models are used to describe the disposition of radio-labelled compounds in regions of interest in the mammalian body, based on a time sequence of measurements from a positron emission tomograph (PET). In this paper we show how closed form solutions for the model equations have been incorporated into a computer program for simulation and parameter estimation. A typical PET data example is included to illustrate the implementation and compare the closed form method with a numerical ode solution method.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compartimentos de Líquidos Corporales
/
Simulación por Computador
/
Tomografía Computarizada de Emisión
/
Modelos Biológicos
Límite:
Humans
Idioma:
En
Revista:
Comput Methods Programs Biomed
Asunto de la revista:
INFORMATICA MEDICA
Año:
1992
Tipo del documento:
Article