Moxifloxacin and biofilm production by coagulase-negative staphylococci.
Chemotherapy
; 50(2): 101-4, 2004 Jun.
Article
en En
| MEDLINE
| ID: mdl-15211086
ABSTRACT
The in vitro activity of moxifloxacin against 41 strains of coagulase-negative staphylococci was determined. A relationship between the activity of moxifloxacin and biofilm formation was detected. Biofilm-producing strains were more resistant to moxifloxacin than biofilm-negative strains. Our global results obtained with six strains of Staphylococcus epidermidis showed that subinhibitory concentrations of moxifloxacin did not significantly modify biofilm formation. On the other hand, moxifloxacin concentrations of 2, 10, 50 and 100 x MIC produced a log decrease in viable count (included in a biofilm) of 0.20, 0.37, 1.10 and 1.69, respectively.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quinolinas
/
Staphylococcus epidermidis
/
Compuestos Aza
/
Biopelículas
/
Antibacterianos
Idioma:
En
Revista:
Chemotherapy
Año:
2004
Tipo del documento:
Article
País de afiliación:
España