Effects of stimulus repetitions on the event-related potential of humans and rats.
Int J Psychophysiol
; 53(3): 197-205, 2004 Aug.
Article
en En
| MEDLINE
| ID: mdl-15246673
ABSTRACT
The present study compared the effects of repeated stimulus presentations on the event-related potential (ERP) of humans and rats. Both species were presented with a total of 100 auditory stimuli, divided into four blocks of 25 stimuli. By means of wavelet denoising, single-trial ERPs were established in both humans and rats. The auditory ERPs were characterized by the presence of two positive and two negative waves in both humans and rats, albeit with different latencies in the two species (P1, N1, P2, and N2). The results showed decreased amplitudes within blocks for the N1, P2, and N2 components in humans and for the N1 and P2 components in rats. Decreased amplitudes across blocks were found for the N2 component in humans and for the P2 and N2 components in rats. In both humans and rats, response decrements within a block were thus most prominent for the early ERP components, whereas the changes across blocks were most prominent for the later components. These results suggest a correspondence of the ERP correlates of elemental stimulus processing between humans and rats. It is further suggested that the observed amplitude reductions may reflect habituation and/or recovery cycle processes.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Potenciales Evocados Auditivos
Límite:
Adult
/
Animals
/
Female
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Humans
/
Male
Idioma:
En
Revista:
Int J Psychophysiol
Año:
2004
Tipo del documento:
Article
País de afiliación:
Países Bajos
Pais de publicación:
HOLANDA
/
HOLLAND
/
NETHERLANDS
/
NL
/
PAISES BAJOS
/
THE NETHERLANDS