MacroH2A, a core histone containing a large nonhistone region.
Science
; 257(5075): 1398-400, 1992 Sep 04.
Article
en En
| MEDLINE
| ID: mdl-1529340
ABSTRACT
A histone, macroH2A, nearly three times the size of conventional H2A histone, was found in rat liver nucleosomes. Its N-terminal third is 64 percent identical to a full-length mouse H2A. However, it also contains a large nonhistone region. This region has a segment that resembles a leucine zipper, a structure known to be involved in dimerization of some transcription factors. Nucleosomes containing macroH2A may have novel functions, possibly involving interactions with other nuclear proteins.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Histonas
/
Nucleosomas
/
Hígado
Límite:
Animals
Idioma:
En
Revista:
Science
Año:
1992
Tipo del documento:
Article