[Immunodiagnosis of endemic mycoses and bronchopulmonary aspergillosis: a multicenter study in Argentina]. / Inmunodiagnóstico de micosis endémicas y aspergilosis broncopulmonar: estudio multicéntrico en la República Argentina.
Rev Argent Microbiol
; 36(2): 68-74, 2004.
Article
en Es
| MEDLINE
| ID: mdl-15470864
In order to contribute to the knowledge of the relative frequency of chronic fungal diseases and assess the performance of diagnostic laboratories in Argentina, a multicenter study was performed with the participation of 25 medical centers located in 12 different provinces and Buenos Aires City. Between 04-01-2000 and 03-30-2001, 965 serum specimens from patients clinically suspected of having histoplasmosis (HP), paracoccidioidomycosis (PCM), coccidioidomycosis (CM) or aspergilosis were analyzed. Agar immunodiffusion tests (IDD) were done locally. All positive and 35% of negative sera were retested in the reference center. Results of laboratories of origin showed 98.8% concordance with those of reference center. Antibodies against any of the etiological agents were detected in 120 specimens from 98 patients. Endemic mycoses (HP, PCM and CM) were diagnosed in 70 patients (71.4%) and aspergilosis in 28 (28.6%). The frequencies of the different mycoses in decreasing order were PCM 47 patients (47.9%), aspergilosis 28 patients (28.6%), HP 13 patients (13.3%) and CM 10 patients (10.2%). The study was carried out on a voluntary basis and some areas of the country were not represented. However, the frequencies were in range with the expected rates in the population under study.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Endémicas
/
Micosis
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
Límite:
Humans
País/Región como asunto:
America do sul
/
Argentina
Idioma:
Es
Revista:
Rev Argent Microbiol
Año:
2004
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
Argentina