Diagnosis of microthrombocytosis and immune-mediated thrombocytopenia in dogs with thrombocytopenia: 68 cases (1987-1989).
J Am Vet Med Assoc
; 200(3): 368-72, 1992 Feb 01.
Article
en En
| MEDLINE
| ID: mdl-1548175
ABSTRACT
The mean platelet volume (MPV) was evaluated in 68 dogs with thrombocytopenia attributable to various causes. Platelet size was high or low in some dogs. The most clinically useful observation was that low MPV (microthrombocytosis) was a specific indicator of immune-mediated thrombocytopenia (IMT) in these thrombocytopenic dogs. All but one case of microthrombocytosis (MPV less than 5.4 fl) was found in dogs with IMT. Microthrombocytosis was detected in 17 of 31 dogs with IMT and appeared at the onset of the disease. Macrothrombocytosis (MPV greater than 9.4 fl) indicated active thrombopoiesis, but was not unique to any disease category. Macrothrombocytosis was detected in 18 of 31 dogs with IMT, 3 of 17 dogs with disseminated intravascular coagulation, and 3 of 9 dogs with primary bone-marrow disease.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Autoinmunes
/
Trombocitopenia
/
Trombocitosis
/
Plaquetas
/
Enfermedades de los Perros
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Animals
Idioma:
En
Revista:
J Am Vet Med Assoc
Año:
1992
Tipo del documento:
Article