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Elevated plasma beta-endorphin/beta-lipotropin concentration following a radius fracture.
Johansen, O; Winge, J; Reikeras, O; Jensen, T; Knutsen, G.
Afiliación
  • Johansen O; Department of Orthopaedic Surgery, University Hospital North Norway, NO-9038, Tromso, Norway. Oddmund.Johansen@unn.no
Scand J Clin Lab Invest ; 64(7): 635-39, 2004.
Article en En | MEDLINE | ID: mdl-15513320
ABSTRACT
Plasma beta-endorphin/beta-lipotropin concentration was assessed soon after a fracture. Blood samples from 14 patients with radius fractures were obtained from both arms soon after admission to the hospital (mean 245 min) after the accident. Follow-up samples were taken after healing of the fractures. Higher plasma beta-endorphin/beta-lipotropin concentrations were found in blood samples taken soon after a fracture in both arms compared with the concentrations after healing of the fracture. At admission, mean beta-endorphin/beta-lipotropin concentrations in the fractured and the contralateral arms were 12.7 pmol/L and 13.2 pmol/L, and after recovery 11.1 pmol/L and 11.5 pmol/L (p = 0.012 and p = 0.041), respectively. The pain decreased according to the visual analogue scale (VAS) (0-10) from 4.64 at admission to 0.58 after healing (p < 0.001). In conclusion, this study showed that beta-endorphin/beta-lipotropin concentrations are increased in both arms following a radius fracture compared to the level after the fracture has healed.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fracturas del Radio / Betaendorfina / Beta-Lipotropina Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Scand J Clin Lab Invest Año: 2004 Tipo del documento: Article País de afiliación: Noruega
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fracturas del Radio / Betaendorfina / Beta-Lipotropina Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Scand J Clin Lab Invest Año: 2004 Tipo del documento: Article País de afiliación: Noruega