Microtubule dynamics.
Curr Opin Cell Biol
; 4(1): 58-65, 1992 Feb.
Article
en En
| MEDLINE
| ID: mdl-1558755
ABSTRACT
Although compelling evidence has been obtained for heterogeneity in the structure of subunits in microtubules, it has not been possible to prove that this results from the presence of tubulin-GDP and tubulin-GTP in polymers. There are reasons to exclude the existence of even a monolayer of tubulin-GTP subunits at microtubule ends. Dynamic behavior appears to be best accounted for by a mechanism in which tubulin-GDP in microtubules exists in two conformations. The mechanism of microtubule-associated protein binding to microtubules and the role of phosphorylation on this reaction are discussed.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Microtúbulos
Límite:
Animals
Idioma:
En
Revista:
Curr Opin Cell Biol
Año:
1992
Tipo del documento:
Article